Which organ secretes renin erythropoietin and calcitriol? (2023)

Asked by: Tess Block

Score: 4.5/5 (72 votes)

The kidneys are important endocrine organs. They secrete humoral factors

humoral factors

Humoral factors are factors that are transported by the circulatory system, that is, in blood, and include: Humoral immunity factors in the immune system. Hormones in the endocrine system.

https://en.wikipedia.org › wiki › Humoral_factor

Humoral factor - Wikipedia

, such as calcitriol, erythropoietin, klotho, and renin into the circulation, and therefore, they are essentially involved in the regulation of a variety of processes ranging from bone formation to erythropoiesis.

Do the kidneys secrete renin and erythropoietin?

The kidney has multiple endocrine roles; it secretes various hormones and humoral factors: the hormones of the renin- angiotensin system (RAS), erythropoietin (EPO), and 1,25 dihydroxy vitamin D3.

(Video) Hormones released from human kidney ( renin | erythropoietin | calcitriol )

What organ gland produces renin?

Renin is an enzyme, also produced by the kidneys, that plays an important role in the renin–angiotensin–aldosterone hormonal system, which helps to control blood pressure.

Do kidneys produce renin?

Renin, enzyme secreted by the kidney (and also, possibly, by the placenta) that is part of a physiological system that regulates blood pressure. In the blood, renin acts on a protein known as angiotensinogen, resulting in the release of angiotensin I.

What do the kidneys secrete?

Hormones The kidneys secrete a number of hormones, which are important for normal functioning of the body. One such hormone is renin, which keeps blood pressure normal. If blood pressure falls, renin is secreted by the kidneys to constrict the small blood vessels, thereby increasing blood pressure.

32 related questions found

What are the 7 functions of the kidney?

The 7 functions of the kidneys

  • A - controlling ACID-base balance.
  • W - controlling WATER balance.
  • E - maintaining ELECTROLYTE balance.
  • T - removing TOXINS and waste products from the body.
  • B - controlling BLOOD PRESSURE.
  • E - producing the hormone ERYTHROPOIETIN.
  • D - activating vitamin D.

What color is urine when your kidneys are failing?

When kidneys are failing, the increased concentration and accumulation of substances in urine lead to a darker color which may be brown, red or purple. The color change is due to abnormal protein or sugar, high levels of red and white blood cells, and high numbers of tube-shaped particles called cellular casts.

Does renin increase BP?

When blood pressure drops for any reason, special cells in the kidney detect the change and release renin into the bloodstream. Renin by itself does not really affect blood pressure.

(Video) Endocrinology - Renal Hormones

How does renin affect the kidneys?

Renin, which is released primarily by the kidneys, stimulates the formation of angiotensin in blood and tissues, which in turn stimulates the release of aldosterone from the adrenal cortex. Renin is a proteolytic enzyme that is released into the circulation by the kidneys.

Do the kidneys activate vitamin D?

The kidneys have an important role in making vitamin D useful to the body. The kidneys convert vitamin D from supplements or the sun to the active form of vitamin D that is needed by the body.

What are the signs of adrenal gland problems?

What are the symptoms of adrenal gland disorders?

  • Upper body obesity, round face and neck, and thinning arms and legs.
  • Skin problems, such as acne or reddish-blue streaks on the abdomen or underarm area.
  • High blood pressure.
  • Muscle and bone weakness.
  • Moodiness, irritability, or depression.
  • High blood sugars.

What causes an increase in renin?

Increased renin release from the juxtaglomerular cells is caused by several conditions: reduction in renal blood flow from heart failure, blood loss, hypotension or ischemia of the kidneys, sodium diuresis (excessive sodium loss in urine), and beta-adrenergic stimulation.

Does renin increase urine output?

This helps to raise the circulating volume and in turn, blood pressure. It also increases the secretion of ADH from the posterior pituitary gland – resulting in the production of more concentrated urine to reduce the loss of fluid from urination.

(Video) Renal Endocrine Function

What are 2 enzymes do the kidneys secrete?

The renal enzyme renin converts angiotensinogen into angiotensin I. The lung enzyme, ACE, converts angiotensin I into active angiotensin II. Angiotensin II is an active vasoconstrictor that increases blood pressure.

Do kidneys regulate pH?

The kidneys have two main ways to maintain acid-base balance - their cells reabsorb bicarbonate HCO3− from the urine back to the blood and they secrete hydrogen H+ ions into the urine. By adjusting the amounts reabsorbed and secreted, they balance the bloodstream's pH.

How do kidneys affect blood pressure?

Your kidneys play a key role in keeping your blood pressure in a healthy range. Diseased kidneys are less able to help regulate blood pressure. As a result, blood pressure increases. If you have CKD, high blood pressure makes it more likely that your kidney disease will get worse and you will have heart problems.

What happens if you have too much renin?

12) Reninoma. Reninomas are rare tumors of the kidney cells that make renin (juxtaglomerular cell tumors). They produce excessive amounts of renin, resulting in severe hypertension, high aldosterone levels, and low blood potassium levels [22, 23].

Why is renin released in hypertension?

The major stimulus for renin release in renovascular hypertension is the severe drop in hydrostatic pressure in the afferent arteriole, the location of the juxtaglomerular renin-secreting granular cells. The pressure drop changes the degree of stretch of these cells which leads to baroreceptor-mediated renin release.

(Video) Endocrine Ability of Heart, Kidney, Liver and Skin

What is the target of renin?

It acts directly on vascular smooth muscle as a potent vasoconstrictor. In addition, it affects cardiac contractility and heart rate through its action on the sympathetic nervous system.

Does ANP increase blood pressure?

ANP binds to three cell surface receptors called ANP receptors. The overall effect of ANP on the body is to counter increases in blood pressure and volume caused by the renin-angiotensin system. It has also been reported to increase the release of free fatty acids from adipose tissue.

How does Raas lower blood pressure?

The RAAS is a complex multi-organ endocrine (hormone) system involved in the regulation of blood pressure by balancing fluid and electrolyte levels, as well as regulating vascular resistance & tone. RAAS regulates sodium and water absorption in the kidney thus directly having an impact on systemic blood pressure.

How do kidneys detect low blood pressure?

The renin-angiotensin system or RAS regulates blood pressure and fluid balance in the body. When blood volume or sodium levels in the body are low, or blood potassium is high, cells in the kidney release the enzyme, renin. Renin converts angiotensinogen, which is produced in the liver, to the hormone angiotensin I.

Is drinking water at night bad for kidneys?

Given the quantity of blood that filters through your kidneys on an hourly basis, those few extra cups are as insignificant to your kidneys as barnacles are to a battleship. So the best time to drink water is not at night. It's when you are thirsty.


What are the first signs of kidney disease?

Signs of Kidney Disease

  • You're more tired, have less energy or are having trouble concentrating. ...
  • You're having trouble sleeping. ...
  • You have dry and itchy skin. ...
  • You feel the need to urinate more often. ...
  • You see blood in your urine. ...
  • Your urine is foamy. ...
  • You're experiencing persistent puffiness around your eyes.


1. Kidney Homeostatic Functions, Animation
(Alila Medical Media)
2. Top 7 Herbs That Detox and Cleanse Your Kidneys Naturally
(Henry's Natural Remedy Tips)
3. Functions of Hormone secreted by Kidney
(Med-Sparkle by Dr. Shariful Halim)
4. Erythropoietin (EPO)
(Medicosis Perfectionalis)
5. TOP 10 Science Backed "SECRETS" to Kidney Health - How to Lower Creatinine Levels Fast
6. Chronic kidney disease - causes, symptoms, diagnosis, treatment, pathology
(Osmosis from Elsevier)
Top Articles
Latest Posts
Article information

Author: Clemencia Bogisich Ret

Last Updated: 02/14/2023

Views: 5635

Rating: 5 / 5 (80 voted)

Reviews: 87% of readers found this page helpful

Author information

Name: Clemencia Bogisich Ret

Birthday: 2001-07-17

Address: Suite 794 53887 Geri Spring, West Cristentown, KY 54855

Phone: +5934435460663

Job: Central Hospitality Director

Hobby: Yoga, Electronics, Rafting, Lockpicking, Inline skating, Puzzles, scrapbook

Introduction: My name is Clemencia Bogisich Ret, I am a super, outstanding, graceful, friendly, vast, comfortable, agreeable person who loves writing and wants to share my knowledge and understanding with you.